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ANALYSIS OF BIOMARKERS IN CHRONIC PERIODONTITIS PATIENTS: A CROSS SECTIONAL STUDY

Dr Zunaira Ghafoor, Dr Ali Abbas Hashmi, Dr Mumtaz Hussain

Introduction: Chronic periodontitis, characterized by inflammation and destruction of periodontal supporting tissues, is one of the most common oral diseases worldwide. Aims and objectives: The main objective of the study is to analyse the biomarkers in chronic periodontitis patients in Pakistan. Material and methods: This cross-sectional study was conducted in Dental Section, Faisalabad Medical University, Faisalabad during February 2019 to July 2019. The data was collected from 100 patients who visited the OPD of the hospital. Purposive sampling method was used in the selection of the study population. Results: The data was collected from 100 patients. Mean values of serum ALP, CPK and Ca are given in table. The mean values of serum ALP (203.92 U/I) and Ca (10.28 mg/dL) was higher in female subjects as compared to the male subjects. These host response factors represent important mediators that can aid in the development of periodontal diagnostics. Conclusion: It is concluded that female subjects are at greater risk of periodontitis and alveolar bone degradation in term of mean values of serum ALP and Ca than the male subjects while the higher mean values of serum CPK in male subjects put them at higher risk of cardio vascular disease than the female subjects.

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