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TITLE:

THE RELATIVE EVALUATION OF USAGE OF DEXMEDETOMIDINE AGAINST FENTANYL FOR ANESTHESIA INTRODUCTION BY PROPOFOL FOR SUPPLEMENT OF LARYNGEAL DISGUISE AIRWAY

AUTHORS:

Dr Ifrah Syed, Dr. Faiza Izhar, Dr. Muhammad Qasim Yazar

ABSTRACT:

Background: Once propofol is exercised laterally by either fentanyl before dexmedetomidine, this offers steady cardiorespiratory illness, reduced airway responses & flat addition of Laryngeal Mask Airway. Aim: The main purpose of our current research stays to associate hemodynamic & breathing limitations, apnea period & case’s reply to Laryngeal Mask Airway addition among dexmedetomidine propofol also fentanyl-propofol mixtures as the main consequence. Subordinate consequence remains to detect slight side effect in intraoperatively & postoperatively phase related by research medicines. Methodology: Potential, dual blind, randomized medical research in 150 fit cases of mutually gender, with ASA grade 1 & 2 remained approved out. Our current research was conducted from January 2017 to October 2018 at the Services Hospital Lahore. Cases remained demographically comparable. Cases stayed randomized to obtain moreover venous dexmedetomidine (2 μg/kg) –propofol(3mg/kg) inoculations- Set-D (n = 75) else Venus fentanyl (2 μg/kg)-Propofol(3mg/kg) inoculations- Set F (n = 75) for Laryngeal Mask Airway addition. Limitations comparable HR, RR, systolic blood pressure, diastolic blood pressure, average arterial blood pressure, oxygen saturation remained noted previously initiation, 35 seconds afterwards initiation, 2, 4, 6, 12, 20, 35, 50 & 65 minutes subsequently addition of Laryngeal Mask Airway. Apnea period remained distinguished. Case’s replies to Laryngeal Mask Airway addition just like jaw flexibility, suppressing else any undertaking remained distinguished. Additional side effects remained similarly detected. Results: In Set-D HR, SBP, DBP Also MABP displayed substantial lessening through research phase subsequent Laryngeal Mask Airway supplement, whereas in Set-F here remained increase in overhead limitations distinguished directly afterwards Laryngeal Mask Airway supplement. In Set-D impulsive breathing remained well conserved also apnea time remained pointedly petite associated to Set-F. Laryngeal Mask Airway addition situations remained satisfactory in cases through mutual set. Occurrence of bradycardia besides hypotension remained developed in cases of Set-D whereas occurrence of vomiting & nausea remained existing in 2 cases of Set-F. Conclusion: Dexmedetomidine 2 μg/kg through propofol 3mg/kg Venus offers valuable result in weakening of hemodynamic reply to Laryngeal Mask Airway addition, improved conservation of impulsive inhalation & suitable Laryngeal Mask Airway addition situations as associated to fentanyl 2 μg/kg by propofol 3mg/kg Venus deprived of main side effects. Key words: Inoculation propofol, inj. dexmedetomidine, fentanyl, laryngeal mask airway, Laryngeal Mask Airway addition.

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