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INVESTIGATION OF MEDICAL AND PATHOLOGICAL PRESENTATION OF BREAST TUMOR AND ASSOCIATION OF THOSE RESULTS THROUGH POSITION OF CANCER MARKERS

Dr Aliya Shaima, Dr Kiran Waseem, Dr Tazmeen Qureshi

Introduction: The breast tumor signs that remain maximum significant in defining treatment remain estrogen receptor, also HER-2/neu. Doctors assess medical also pathologic enactment in addition appearance of estrogen receptor, also HER-2/neu in main cancer to measure prognosis also allocate treatment. Aims and objectives: To investigate medical also pathological performance of breast tumor in addition to associate those results through position of cancer signs. Materials and methods: 50 breast tumor cases that appeared department of general surgery, Lahore General Hospital Lahore amongst September 20016 to July 2018 remained involved in our current research. Altogether cases remained acquiesced to comprehensive medical inspection in addition inquiries counting FNAC to approve illness in addition to discover medical period. Altogether facts/information of 50 cases remain investigated to discover whether here remains any association amongst medical presentation, pathological production also cancer signs. An effort remained completed to associate results of our research through existing Pakistani also worldwide researches. Results: In our current research common vases offering by carcinoma breast fit to 6 also 7 period. The current reflection about period of illness exposed that period II also phase III illness remained alike dispersed. In total 15 cases in age set 23-45yrs eight offered through stage II in addition residual 8 through phase III, 14 cases in age set 42-63yrs offered by phase II illness while 12 offered by phase III illness. The current remark concerning phase of illness exposed that 25 remained in pathological phase II also 18 remained in phase III. Popular of these cases (16) remained in phase IIB. Mainstream (25 out of 45) of cases remained obtainable through pN0 standing, 12 by pN1, in addition 8 through pN2 phase. Medically node undesirable respondents remained 20 out of 50. Nonetheless pathologically node negative patients were 24 in total of 50. 92% of cases having medical phase II also stage III B remained in identical phase in pathological enactment, everywhere as in phase III A solitary 54% endured in identical phase. This remains detected that variation of medical period to pathological period remains owing to variation in nodal position. Conclusion: Most of cases remained triple negative sovereign of age, nodal rank, medical, pathological phase also histological kind. Difficult for ER, PR, Her2neu receptor rank remained suggested in altogether cases having breast tumor to enable neoadjuvant also adjuvant treatment also for prognostication. Keywords: Nitrating duct cell carcinoma, hormone receptors. Triple negative cancers.

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