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TITLE:

ANALYSIS OF COMPARISON OF PULMONARY FUNCTION TEST IN CONTROLLED AND UNCONTROLLED TYPE 2 DIABETES MELLITUS

AUTHORS:

Shumaila Ashraf, Isma Komal, Maryam Abdul Ghaffar

ABSTRACT:

Introduction: Pulmonary complications of diabetes mellitus (DM) have been poorly characterized. Some authors have reported normal pulmonary functions and even concluded that spirometry is not at all necessary in diabetic patients. Objective: Compare Pulmonary function test in controlled and uncontrolled type 2 diabetes mellitus patients. Data Collection: This cross sectional study was conducted in Basic Health Unit Malikpur District Narowal during March 2019 to September 2019. All patients and controls who fulfil selection criteria were enrolled in the study. Informed consent was obtained from each patient. Demographic profile was also be taken. Only those patients whose fasting blood sugar were >126 mg/dl or random blood sugar >200 mg/dl were selected. The HbA1c was also estimated in order to differentiate between controlled (<7) and uncontrolled diabetes (>7). Results: In this study no statistically significant difference was seen between mean ranks for FVC [Group-A:86.91, Group-B: 74.00 & Group-C: 83.59], FEV1 [Group-A:88.44, Group-B: 80.56 & Group-C: 75.50] and FEF(25-75) [Group-A:87.53, Group-B: 80.73 & Group-C:76.23] among the study group. However for FEV/FVC significantly differ across the groups. i.e. [Group-A:98.18, Group-B: 109.41 & Group-C: 36.91]. Multiple comparison test showed that not statistically difference was seen for FEV/FVC between Group-A and in Group-B patients. However between Group-A and Group-C and Group-B and Group-C statistically significant difference was seen. Conclusion: Results of this study showed that uncontrolled diabetes adversely effects pulmonary function and causes significant lung function impairment.

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