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PREVALENCE OF MIDDLE VESSELV ASCULITIS AMONG PATIENTS SUFFERING FROM TUBERCULOSIS OF CNS

Farial Javed, Adnan Faiz, Maheen Fatima

Objective: The aim of this research work is to find the prevalence of the middle artery vasculitis in the patients suffering from tuberculosis of the central nervous system which is very rare and uncommon in this particular literature. Methodology: This study was a prospective research work based on observations at DHQ/Teaching Hospital D.G Khan, from June 2016 to December 2018. (Only 4 patients appeared in the Hospital directly; among the other 4 patients, 3 were visitor of primary healthcare center which was not providing the facilities of admission so those patients admitted in Hospital and other the 1 patients were getting treatment from private institutes but patients were not able to fulfill the requirement of expenses of those hospitals so these patients also visited the Hospital). Results: We analyzed a sum of total 8 patients suffering from TB of CNS who were present with stroke as an outcome of the middle artery infarction in all 8 patients. There were 4 male & 4 female patients with a range of age from 7 to 54 years. one participant was present with stroke at appearance and one patients developed after eight weeks of the treatment whereas other patients got stroke within one to four weeks. No patient was present with evidence of extrneural TB & 2 patients were available with the other factors of stroke which ruled out as a reason at that time for the stroke. Two patients were present with vasculitis of small artery in addition to the large stroke. One patient died, one patient got complete recovery and remaining eight patients were able to recover partially. Conclusion: Though vasculitis of small vessel is the common complication of TB of central nervous system, vasculitis of middle vessel is common and it plays important role for the high rate of morbidity as well as mortality due to this particular complication. Keywords: CNS, Vasculitis, Tuberculosis, Stroke, Infarction, Nervous System, Neurology.

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