ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

FREQUENCY OF THYROID PATHOLOGIES AT TERTAIARY CARE UNIT

Dr. Munazah Aizaz, Dr. Syed Moeen Riaz, Dr Anwaar Yousaf, Dr Ahmed Ali, Dr Rizwan Bajwa

Objectives: Endocrine diseases are common, particularly those of the thyroid gland. The pathophysiology of many thyroid diseases relates to TSH, T3 and T4. The most important chemical marker of thyroid function is TSH. Hyperthyroidism is the result of low TSH profile, whereas high value leads to hypothyroidism .Thyrotoxicosis is the hyper-metabolic condition confirmed by estimation of free T4 (fT4), free T3 (fT3) .Thyrotoxicosis or hyperthyroidism is an excess of thyroid hormone caused by an over active thyroid tissue or is the consequence of additional synthesis and liberation of thyroid hormone. Aim of the current study is to determine the frequency of thyroid pathologies among the patients visiting Jinnah Hospital Lahore. Methods: It is an observational study done at main medical OPD of Jinnah Hospital Lahore. In this study we evaluated 300 patients from May 2019 to July 2019.This study was approved by the ethical committee of Jinnah hospital. The blood samples were collected, followed by their analysis for triiodothyronine (T3), tetraiodothyronine (T4) and thyroid stimulating hormone (TSH). All the patients were interrogated with the help of a preformed questionnaire. A brief history including sociodemographic details, family history of thyroid disease were also asked. All necessary laboratory investigations were performed including a lipid profile, complete blood count, LFTs, etc. Results: among 300 patients, there were 180 female (60%) and 120 male (40%) with female to male ratio of 1.8:1.2. Majority of patients were in age group of 25-55. The results obtained revealed that female gender has categorically significantly high percentage of occurrence of thyroid abnormality as compared to male gender (76.4% vs. 23.6%). Results regarding locality distribution of the patients depicted that majority of those belonged to the local population of Lahore. Conclusion: Thyroid diseases are more common in females as compared to males. The most probable causes could be lactation and pregnancy and hormone changes. Keywords: Thyroid dysfunction, euthyroid, hypothyroid, hyperthyroid.

FULL TEXT