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ANTIMICROBIAL ACTIVITY OF CRUDE METHANOLIC EXTRACT AND VARIOUS FRACTIONS FROM PARROTIOPSIS JACQUEMONTIANA (DCNE) REHDER

Muhammad Rawan, Bashir Ahmad, Abdul Wahab, Muhammad Kamran, Sohail Ahmad, Benish Sial, Yaqoob ur Rehman, Farah Gul, Shafaatullah, Arshad Farid*

Plants contain such substances which can be used to treat different kind of disease conditions. These medically important substances are known as phytoconstituents or phytochemicals and they have the major responsibility of protecting the plant against infectious diseases and protect them from the attack of the pests. Crude Methanolic Extract (CME) and different polarity-based solvents fractions of P. jacquemontiana was evaluated for biological activities. Efficiency of each extract was checked. CME fraction gave maximum efficiency, followed by ethyl acetate, and n-hexane was least efficient. All the extracts were showed more or less effect on different bacterial strains and have different inhibition zone. CME, n-hexane and ethyl acetate (EA) extracts were showed effect on S. aureus and E.coli strains, and do not showed any effects against K. pneumoniae. Extracts were also checked on different fungal strain in which Ethyl acetate and CME of stem were showed maximum zone of inhibition against A. Flavus strain and A. nigar do not have effected by any extracts. Finding suggest that instead of fraction CME have greater effect on antimicrobial agents. Key words: P. jacquemontiana, CME, n-hexane and ethyl acetate, antifungal, antibacterial.

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