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THYROID PROFILE: A COMPARATIVE STUDY BETWEEN PRE-ECLAMPTIC AND NON-ECLAMPTIC WOMEN

Mehwish Memon, Mahak Memon, Khadim Hussain, Momna Khan, Faisal Irshad, Madiha Shah

This Case-control study was conducted at clinical laboratory in Isra University Hospital and LUMHS Hospital Hyderabad from January 2015 to June 2015 on 45 healthy pregnant women as group-I (control) and 45 pre-eclamptic patients as group-II (cases).The purpose behind was to evaluate serum thyroid profile in blood samples of healthy pregnant women and pre-eclamptic patients and to determine the possible role of thyroid profile in patients of pre-eclampsia. After consent and biodata ,blood samples for serum thyroxin T4 Serum tri-iodothyronine T3 and TSH (serum thyroid stimulating) were collected from both cases and controls and analyzed at Isra Research lab. There was significant difference between the serum TSH levels among the two groups p-0.0001 while no significant difference was observed in serumT3 and T4 levels among pre-eclamptic and non-pre-eclamptic women p-0.58 and 0.37 respectively. Conclusion: Serum thyroid stimulating hormone (TSH) was raised in pre-eclamptic women as compared to non-eclamptic women, while non-significant difference exists in serum T3 and T4 levels between the two. Key Words: Pre-eclampsia, T3, T4, TSH, Pregnancy.

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