Gao Ke，Syed Haider Abbas, Zainab Awais，Hang Hang，Guo Qi Xiu ，Zhao Wu
Objective To investigate the related factors of mycoplasma pneumoniae pneumonia (MPP) associated with central nervous system(CNS) damage , and to provide evidence for its early diagnosis and treatment. Methods Children with mycoplasma pneumoniae who were hospitalized in the department of Pediatrics of our hospital from November 1, 2015 to July 31, 2019.were selected as the research objects, 113 cases in the group with no central nervous system damage of mycoplasma pneumoniae pneumonia (control group) and 24 cases in the group with central nervous system damage of mycoplasma pneumoniae pneumonia (observation group) were compared. Results There were significant differences in fever degree (℃), high MP antibody titer (≥1:160) and CRP between the two groups （P <0.05）. There were no statistically significant differences between the two groups in age, gender, delivery mode or feeding mode（P ＞0.05）.Conclusion elevated CRP may be an independent risk factor for MPP combined with central nervous system damage in children, while high MP titer may be a protective factor. Key words: mycoplasma pneumoniae pneumonia; central nervous system damage; correlative factors; children.