::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

EVALUATION OF IMPACTS OF FIBROMYALGIA ON PARITY, GRAVIDITY, BREASTFEEDING AND MENARCHE AGE

AUTHORS:

Dr Ozair Bilal Ahmed, Dr Usama Bilal Ahmad, Dr Shahryar Aamir

ABSTRACT:

Objectives: Fibromyalgia Syndrome is a complication normally influencing the females in their fertility age. However, there is no research work on the association of pregnancy and Fibromyalgia Syndrome. Impact of Fibromyalgia Syndrome on pregnancy course is poorly examined in present literature. In this research work, we examine the impacts of Fibromyalgia Syndrome on parity, breastfeeding duration, gravidity and menarche age. Methodology: In this prospective research work, we included 187 non-pregnant females attending the Shaikh Zayed Hospital Lahore from April 2020 to August 2020. 111 patients among them were identified with presence of Fibromyalgia Syndrome according to ACR (American Rheumatology Association) criteria and we categorized them in Group-1. 76 healthy females without pregnancy were the participants of Group-1. We asked from all the females about their marriage age, menarche age, parity, gravidity and breastfeeding duration with help of questionnaire. We recorded the BMI of the patients. We evaluated the parameters about depression with the help of BDS (Beck Depression Scale). Results: Mean age of the patients in Group-1 was 39.040 ± 9.210 (Fibromyalgia Syndrome) and average age of participants of Group-2 was 38.470 ± 9.650 years, 1st menarche age was 13.280 ± 1.380 years in Fibromyalgia Syndrome group and 13.590 ± 1.540 years in Group-2. Marriage age in patients of Group-1 was 20.10 ± 3.62 & 20.69 ± 3.9 years for the group of controls, correspondingly. We found no significant difference between the values of BMI (Group-1, 27.760 ± 4.950; Group-2 26.9 ± 4.56 kg/m2). Results of examination were similar in both groups in terms of parity, gravidity and duration of breastfeeding with no important difference statistically (P=0.2520, 0.0930, 0.0750, respectively). We found the significant difference in the parameters of depression. Results of BDS were different for both groups, higher in the patients of Group-1 (P=0.000). Conclusion: There was occurrence of Fibromyalgia Syndrome as a result of symptoms like disorder of mood, anxiety, sleep disorders and hormonal alterations; there is no establishment of the exact cause. This complication usually occurs in fertility age of the females. In accordance with the results of this research work, there is no adverse effect of Fibromyalgia Syndrome on the outcome of parity, gravidity and breastfeeding duration of females. There is need of further research works to examine the effects of Fibromyalgia Syndrome on the pregnancy course. KEYWORDS: Fibromyalgia Syndrome, Breastfeeding, Parameters, Depression, Gravidity, Parity, Menarche Age, Complication, Outcome, Depression.