::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ACUTE COMPLICATIONS AND MORTALITY SPECTRUM IN BACTERIAL MENINGITIS

AUTHORS:

Muhammad Farhan Zafar Chaudhary, Muhammad Atique Arshad, Talha Shabbir

ABSTRACT:

Aim: The aim of the study was to obtain data on the incidence of acute complications and mortality associated with bacterial meningitis in children. Patients and Methods: This was a descriptive observational study conducted at the Pediatric department of Sir Ganga Ram Hospital, Lahore for period of 6 months from January 2020 to June 2020. All patients aged 1 month to 10 years with probable bacterial meningitis were included in the study. The information was saved in a pre-designed proforma form and the data was analyzed using SPSS version 16. Results: Sixty patients were enrolled in the study. There were 48 (80%) men and 12 (20%) women with an M: F ratio of 4: 1. About three-quarters of patients (76.67%) were under the age of 1 year (46/60). Complications occurred in 21 (35%) patients during hospitalization. The most common complication was convulsions after four days of illness (21.7%), followed by subdural effusion (11.9%), hydrocephalus (10%), palsy of the cranial nerve (8%), hemiplegia (7%), increased intracranial pressure (3%). Ten patients had more than one complication. There was only one death (1.67%) and one patient missed a doctor. In this study, the history of more than 7 days before the hospital visit was significantly associated with an increased incidence of acute complications of meningitis (p = 0.002). Conclusion: Seizures, subdural effusion, and hydrocephalus are the most common acute complications in patients with meningitis in this study. There is an increased risk of acute complications in patients with long-term symptoms. Key words: bacterial meningitis, meningitis, convulsions.