::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

RELATION OF HIGHLY SENSITIVE C – REACTIVE PROTEIN LEVELS WITH CORONARY ARTERY DISEASE SEVERITY

AUTHORS:

Dr Muhammad Asadullah, Dr Muhammad Adil, Dr Ahmad Qadri

ABSTRACT:

Coronary artery disease is a major component of cardiovascular disease and the leading cause of death in developing countries. The disease is characterized by a long asymptomatic period of atherogenesis resulting in an increase in plaque and a symptomatic period of angina or a clinical coronary event. In the present study, levels of the highly sensitive C-reactive protein (Hs-CRP) were determined in patients with coronary artery disease with one-, two- and three-vessel disease and compared with the severity of the disease. A moderate correlation was found with a p value below 0.001. It is suggested that the Hs-CRP should be performed in all patients with significant thrombotic atherosclerosis. These tests are relatively inexpensive and detect a predisposition to future events such as acute MI (myocardial infarction) in patients with coronary artery disease. Key words: coronary artery disease (CAD), very sensitive levels of C-reactive protein (Hs-CRP)