::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO DETERMINE THE HEPATITIS B AND C VIRAL INFECTIONS AMONG BLOOD DONORS

AUTHORS:

Dr Noor Ul Ain, Dr Mohsin Nadeem, Dr Ahmed Tariq

ABSTRACT:

Background: The hepatitis B virus and the hepatitis C virus are a major public health problem worldwide, affecting billions of people. There is no information available on this in the investigated area. Aims: The aim of the study was to assess HBV and HCV seroprevalence among blood donors. Place and Duration: In the Hematology and Medicine Unit-II of Services Hospital Lahore for one-year duration from May 2019 to May 2020. Method: A cross-sectional study of blood donors was conducted. Five milliliters of blood samples were taken and subjected to ELISA tests to detect hepatitis B surface antigen and hepatitis C antibody. Chi-square tests and Fisher tests were used for analytical evaluation. Results: Of the 2,384 blood donors tested, 108 (4.5%) were seropositive for at least one of the two markers of hepatitis, five of which were co-infected. The prevalence of HBs Ag and anti-HVC was 4.11% and 0.63%, respectively. High HBV seropositivity (8.3%) was found in> 45 years, and the positive HBV result was significantly higher among men (4.4%) than women (1.45%) (P = 0.04). The incidence of HCV was significantly higher at> 45 years of age (2.5%, p = 0.01). Conclusion: The prevalence of HBV and HCV was high, and diseases continued to be a serious health problem for older people in the study area, warning of public health intervention as soon as possible. Keywords: Pakistan, Hepatitis B virus, Hepatitis C virus, Seroprevalence, Blood donors.