::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

FREQUENCY OF HEPATITIS B IMMUNIZATION GIVEN TO INFANTS BORN TO HEPATITIS B INFECTED MOTHERS

AUTHORS:

Dr Sara, Dr Qindeel Hira Qureshi, Dr Aqsa Amin

ABSTRACT:

Background: Globally the rate of chronic infection of Hepatitis B ranges from 0.1% to 20%1-3. The prevalence of Hepatitis B worldwide is divided into three categories, i.e. High (>8%), Intermediate (2%-7%), Low (<2%). In Pakistan, only 54% of the eligible children have received all the three doses of hepatitis B vaccine 9. Aim: To know the frequency of Hepatitis B vaccination given to infants at birth born to Hepatitis B positive mother in year 2019. Materials and Method: We conducted our study in three hospitals of Lahore; both public and private i.e. Amna medical Centre, Mayo Hospital and Jinnah Hospital. The subject of our study was infant born to hepatitis B positive mother. The study design was retrospective cohort in which we have compared the public and private hospitals of Lahore. We checked all the record for one year from January 2019 to December 2019. A total number of 7,842 patients record was checked which 112 pregnant women were found hepatitis B positive. All the data was entered in excel sheet. Mean and standard deviation were calculated. Bar graphs were designed for results. Results: A total number of 7,842 files of pregnant women were checked in three hospitals of Lahore. Out of which 46 (2.5%) were found Hepatitis B positive. 2 (4.3%) infants were screened for Hepatitis B. 38 (82.6%) infants received Hepatitis B vaccine including 30 (65.2%) infants received both Hepatitis B vaccine and immunoglobulin’s while 8 (17.3%) infants didn’t received any vaccination. Conclusion: The situation indicates a strong need of implementing hepatitis B vaccination dose at birth and changing the overall immunization mechanism. Keywords: preventable disease, chronic infection, immunization mechanism, immunoglobulin.