Sadaf Zahra, Uroosa Zahara, Syeda Sabah Zahra
It is pervious observed that the type 1 diabetes is a type of diabetes in which patient have the higher level of sugar and glucose level. It is caused by the two main auto antibodies anti gad and anti ia2. It is observed that these two antibodies are responsible for making of insulin due to these two auto antibodies the destruction of beta cells begin that cause no observance of insulin in the blood cell. It is also observed that the what glycated hemoglobin what it effects in a body. It is also observed in this study that the how glycated hemoglobin what its plays a role in a glycemia in a diabetes. It is also observed in this study that the how the environmental and the genetic factors effect on all that. It is also observed in previous study that the how the genes of parents and grandparents effects on the child it is also observed that the child from the previous background of type 1 diabetes have greater than the 11 percent more chances of diabetes in a future. It is also observed that the patient have from type 1 diabetes had more chances of the diabetes in a future. It is also observed in the previous studied that the child are not from the diabetes background have less chances of diabetes in a future. For the calculating of that the genetic determinants we use a study called the genome wide study. For the calculation for the different study we use the analysis methods it is called the Meta analysis. Keywords: Glycated hemoglobia, glycemia, glycated, diabetes background, meta-analysis, genetic determinants, analysis method, future chances of diabetes.