::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

News Updates Latest Volumes: COSMOS IMPACT FACTOR (2018)- 4.153, GLOBAL IMPACT FACTOR(2014) - 0.384, (2015) - 0.437, Indo American Journal of Pharmaceutical Sciences,

ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

ANALYSIS OF SINO-NASAL ABRASIONS RELATED WITH CHRONIC RHINOSINUSITIS THROUGH HISTOPATHOLOGY AND ITS COMPARISON WITH THE DIAGNOSIS THROUGH CT SCAN

AUTHORS:

Farah Naseer, Shama Naseer, Jehan Zaib Naseer

ABSTRACT:

Objective: CRS (Chronic Rhino Sinusitis) is a condition with inflammation of paranasal sinuses and lasting of nasal passage greater than 3 months either without or with the sino-nasal polyps. The aim of this research work was to examine the sino-nasal abrasions related with Chronic Rhino Sinusitis in accordance with the results of histopathology, to compare between the diagnoses conducted clinically and histopathological and provide a comparison between diagnoses with radiology and histopathology of sino-nasal abrasions. Methodology: This retrograde research work was carried out with the examination of the electronic records of eighty-two patients identified with chronic rhino sinusitis nasal polyps. All the patients had to undergo sinus surgery through endoscopy and histopathological assessment of biopsies with surgical intervention. We used the SPSS program for the statistical analysis of the collected information. We also performed the comparison between the histopathological and clinical diagnoses. This research work was carried out at Allied / DHQ Hospital Faisalabad. Results: Out of eighty-two patients, the range of the age of the patients was from 4 to 90 years with an average age of 34.48 ± 17.74 years. There were 54.880% female patients. Most common lesions were inflammatory polyps (31.40%), followed by allergic polyps (30.50%). NPC (Naso-pharyngeal Carcinoma) was detected in total 9.80% abrasions and all of these were unilateral. The findings showed consolidate compatibility between diagnoses conducted clinically and histopathological. (P<0.0010, kappa= 0.2150), and strong compatibility between diagnosed conducted as radiologically and through histopathology (P=0.0070). Conclusion: Most common benign abrasions (bilateral) are the inflammatory & allergic polyps related with the chronic rhino sinusitis, which can be diagnosed rightly in majority of the patients. There are high malignancy rates in the unilateral nasal polyps and these should be examined meticulously with the help of histopathology and endoscopy. There are some pitfalls in the diagnosis of fungal sinusitis with the help of CT (Computed Tomography). Keywords: Computed Tomography, Diagnosis, Nasal Polyp, Histology, Inflammatory, Allergic, Chronic Rhino Sinusitis.