::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

COMPARISON OF PREGNANCY OUTCOMES IN INFERTILE WOMEN WITH POLYCYSTIC OVARIAN SYNDROME

AUTHORS:

Dr. Attia Bukhari, Dr. Lubna Munir, Dr. Laraib Iqbal

ABSTRACT:

This present study aimed to investigate the pregnancy outcomes in infertile women with polycystic ovarian syndrome. This was a prospective study conducted at Nishtar Hospital, Multan during 2019 to 2020. This study was based on the local female population of Pakistan. Total number of selected patients was 50. This study was done according to the rules and regulations of ethical committee of hospital. The patients were selected from the outpatient department of Obstetrics and Gynecology by the researcher. A total of 100 patients with the polycystic ovary syndrome were randomly assigned to a treatment group and the two groups were well matched at baseline. The mean age in this study is 28 years. In Group A, the BMI is 35.1 and in group B the mean BMI is 35.2In the age group 25-29 years, in group B (Clomiphene Citrate), treatment was found to be efficacious in 24.5% patients, while it was efficacious in 48.1% (n=26/54) in group A (Letrozole) patients. Having a significant p-value 0.013 (<0.05), implying significant better results with Letrozole in terms of successful pregnancies. In conclusion, our study showed that letrozole was superior to clomiphene as a treatment for an ovulatory infertility in women with the polycystic ovary syndrome. Letrozole was associated with higher live-birth and ovulation rates.