::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ASSOCIATION BETWEEN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND RAISED CAROTID INTIMA-MEDIA THICKNESS (CIMT)

AUTHORS:

Dr. Fatima Safdar, Dr. Muhammad Haris Sarwar, Dr. Ghulam Mustafa

ABSTRACT:

Objective: To determine the association between nonalcoholic fatty liver disease (NAFLD) and raised carotid intima-media thickness Materials & Methods: This cross-sectional study was conducted at Department of Medicine, Bahawal Victoria Hospital, Bahawalpur from July 2019 to December 2019 over the period of 6 months. Total 109 patients either male or female having age from 30-45 years having nonalcoholic fatty liver disease were selected for this study. Results: The mean age in cases group was 37.51 ± 4.07 years and in control group was 37.45 ± 4.03 years. Out of 218 patients, 136 (62.39%) were males and 82 (37.61%) were females with male to female ratio of 1.7:1. Frequency of raised CIMT in cases group was seen in 62 (56.88%) while in control group was seen in 41 (37.61%) cases with a p-value of 0.004 and odds ratio of 2.1879 which is statistically significant and shows a positive association between NAFLD and raised CIMT. Conclusion: This study concluded that the frequency of raised carotid intima-media thickness is higher in patients with non-alcoholic fatty liver disease and shows the positive association between nonalcoholic fatty liver disease (NAFLD) and raised carotid intima-media thickness. Keywords: Liver, alcohol, fatty, carotid.