::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

CLINICAL FEATURES OF ENTERIC FEVER IN DIFFERENT AGE GROUPS

AUTHORS:

Dr. Tariq Mahmood, Dr. Muhammad Asif Jappa, Dr. Itzaz Hussain

ABSTRACT:

Objective: To know the clinical manifestations of enteric fever on the basis of age difference in <5 years and ≥ 5 years old children. Methods: This study was conducted to know the clinical profile of enteric fever patients admitted in pediatric unit of District Headquarters Hospital, Jhang for one-year duration from March 2019 to March 2020. A total of 36 patients between the age of 9 months to 12 years with fever with Widal positive and/or with culture grown salmonella were included. Results: The mean age of presentation was 5 ± 3 years. The ratio of men to women was 2: 1. The frequent clinical symptoms were fever (100%), vomiting (38.8%), abdominal pain (27.77%), cough (27.77%), diarrhea (19.44%), hepatomegaly (80.55%), splenomegaly (47.22%), relative bradycardia (13.88%) and rose spots (8.33%). None of the patients were constipated. In the age group <5 years, diarrhea was more frequent, while the relative bradycardia was observed in the age group ≥5 years. Of all the first-line antibiotics in 31 (86.11%) ceftriaxone, in 4 (11.11%) ciprofloxacin, cefotaxime in one (2.7%) were given. Treatment failure with first-line antibiotic was reported in 30.5% patients. Complications occurred in 6 (16.66%) patients, including 2 (33.32%) had serious inflammation, 1 (16.67%) each had osteoarthritis, splenitis abscess and shock. 34 (94.44%) children recovered, 1 died and 1 was lost to follow. Recovery was faster in the <5 years group compared to ≥5 years. 30% of our patients had third-generation resistance cephalosporin as first-line antibiotics. Conclusion: Diarrhea was more common in the age group <5 years, whereas relative bradycardia was only seen in the age group ≥ 5 years. In any case, there was no constipation. Clinical symptoms such as fever vomiting, abdominal pain, cough, diarrhea, enlarged liver Both age groups had splenomegaly and rose stains. Key words: Intestinal Fever, Relative Bradycardia, Diarrhea.