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Nishad V M, Dr Prasobh G R, Mrs Sheeja Rekha A G, Visal C S
The β-lactam antibiotics are a large class of diverse compounds used clinically in both the oral and parenteral forms. The β-lactam antibiotic agents have become the most widely used therapeutic class of antimicrobials because of their broad antibacterial spectrum and excellent safety profile. Reports of drug–drug interactions with the β-lactam antimicrobials are a relatively rare phenomenon, and when interactions do occur, they are generally minor. β-lactam antibiotics act by inhibiting the bacterial cell wall biosynthesis; they are the most available antibiotics which treat a number of bacterial infections. For having a global positive impact on health by treating bacterial infections, penicillin and other β-lactam antibiotics are arguably considered the most important drugs ever. Key words - Resistance to β-lactam activity