::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

UPPER GASTROINTESTINAL TRACT LESIONS INCIDENCE AS PERCEIVED ON ENDOSCOPIC BIOPSIES IN PATIENTS ATTENDING THE HOSPITAL WITH IRON DEFICIENCY ANEMIA

AUTHORS:

Dr Aazib Irshad, Dr Ans Dastgir, Dr Muhammad Umar Zubairi

ABSTRACT:

Aim: To determine the frequency of various lesions of the upper gastrointestinal tract detected in patients with iron deficiency anemia following endoscopic biopsy. Methods: This was a cross-sectional study conducted at the Medicine Unit-II of Jinnah Hospital Lahore for one-year duration from April 2019 to April 2020. All patients diagnosed with iron deficiency anemia and positive fecal occult blood tests were included in the study. Patients who had a history of gastric surgery and patients who refused to participate were excluded. After obtaining informed consent, endoscopy of the upper gastrointestinal tract in all selected patients was performed by a gastroenterologist consultant, and biopsies were sent to the laboratory for histopathological examination in order to make a proper diagnosis. In addition to collecting basic demographic data, all these findings have been recorded in a short, structured proforma form. Data were analyzed using SPSS v.16.0. Qualitative data was presented as% age and graphs, while mean ± standard deviation was used for quantitative analyzes. Results: The mean age of our patients was 29.8 ± 6.7 years. There was an overall predominance of women (71.61%). Of the 310 patients with iron deficiency anemia, changes in the upper gastrointestinal tract were found in 144 (46.45%), while no morbidity was found in 166 (53.55%). Regarding the incidence of various lesions of the upper gastrointestinal tract, 43 (29.86%) had erosive gastritis, 48 (33.33%) had gastric ulcer, 27 (18.75%) had erosive duodenitis, and 26 (18.06%) had gastric cancer detected by endoscopic examination. biopsy. Conclusion: The frequency of changes / disorders of the upper gastrointestinal tract found in our patients with iron deficiency anemia was 46.4%. The most common lesion of the upper gastrointestinal tract was gastric ulcer, followed by erosive gastritis, erosive duodenitis, and gastric cancer. Key words: gastrointestinal bleeding, capsule endoscopy, biopsy, iron deficiency anemia