::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

News Updates Latest Volumes: COSMOS IMPACT FACTOR (2018)- 4.153, GLOBAL IMPACT FACTOR(2014) - 0.384, (2015) - 0.437, Indo American Journal of Pharmaceutical Sciences,

ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

URINARY SODIUM AND POTASSIUM DISCHARGE AND DANGER OF HYPERTENSION IN PAKISTANI POPULATION

AUTHORS:

Rameesha Azam, Nosheen Farooq, Manayal Ejaz

ABSTRACT:

Aim: Dietary sodium admission is related with pulse and hypertension hazard. Be that as it may, the majority of the contemplates have been directed in whites and it isn't clear regardless of whether the impacts exist in Asian populaces. The reason for the current investigation was to explore the part of 24-h urinary sodium discharge and hypertension hazard among ethnic Pakistani. Methods: One thousand 500 and twenty moderately aged and old members who were free from hypertension at benchmark and had accessible pee electrolyte data. Our current research was conducted at Mayo Hospital, Lahore from May 2019 to April 2020. During a middle 8.94 long stretches of development (interquartile rangeU4.08–8.05 years), we archived 667 instances of occurrence hypertension. Results: The multivariate hazard was 4.27 (96% certainty intervalU1.01-1.58; PU0.044) for those in the highest quartile of sodium urine flow compared to those in the next highest quartile. A critical J-shaped relationship between urinary sodium flow and the danger of hypertension was observed, with the direct link test being rejected (PU0.046). Members who were in the most notable quartile of sodium urine output and higher standard blood pressure had an increased risk of hypertension of 3.46 (96% certainty interval U1.73-4.23) in contrast to those in the lowest quartiles of sodium urine output and lower blood pressure. Conclusion: Urinary sodium discharge was linked to the danger of hypertension in ethnic Pakistani. Urinary sodium output, as a marker of dietary sodium intake, may be useful for a thorough assessment of the risk of hypertension in Asian populations. Keywords: Urinary Sodium, Potassium Discharge, Hypertension.