Dr. Ameer Hussain Shah, Dr. Muhammad Shahzad Alamgeer, Dr. Muhammad Suhaib Abbas
The main objective of the study is to analyse the early surgical therapy of infective endocarditis in children in Pakistan. This cross sectional study was conducted in Bahria University Medical and Dental College, Karachi during January 2019 to January 2020. The data was collected from 100 patients of age range 10 to 15 years. Five ml of fasting fresh blood sample was taken from all the patients. Then this blood was centrifuged at 4000 rpm for 10 minutes. The data was collected from 100 patients of both male and females. The mean age was 12.52±5.65 years. The mean values of serum ALP (203.92 U/I) and Ca (10.28 mg/dL) was higher in female subjects as compared to the male subjects. The noted in females and positive in male subjects. Significant correlation of CPK (p = 0.001) was found with age in females while positive correlation was found for CPK in both the groups with other variables. It is concluded that the association between dental procedures and the risk of IE remained insignificant after adjustment for antibiotic use, indicating that dental procedures did not increase the risk of IE.