::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

THE POSSIBILITY OF CARDIAC COMPLICATIONS IN PATIENTS WITH THYROTOXICOSIS

AUTHORS:

Dr Muhammad Umar Zubairi, Dr Hafiza Qaria Tayyeba Younus, Dr Muhammad Mansoor Younas

ABSTRACT:

Aim: One of the major complications of thyrotoxicosis (TS) is heart disease, including arrhythmias. This study aims to determine the cardiac complications of thyrotoxicosis. Methodology: It was a prospective study conducted over a period of 1 year in the Endocrinology department of Jinnah Hospital Lahore for one-year duration from May 2019 to May 2020. All patients with clinical and / or biochemical manifestations of TS were followed up and examined for clinical and laboratory signs of thyrotoxicosis cardiac complications. Results: A total of 103 people with TS were found, which gives the incidence rate of 27%. The male-to-female ratio in patients with thyroid disease was 1: 5. The incidence of hypertension, arrhythmia, and heart failure was 53%, 25%, and 42%, respectively. Patients with cardiac complications of TS had clinical features of thyrotoxicosis of various severity. Echocardiographic features documented in some people with heart failure include dilation of the heart wall, impaired systolic function, decreased ejection fraction, and fractional shortening. Conclusion: Thyrotoxicosis is a significant cause of cardiac morbidity. Keywords: thyrotoxicosis, cardiac complications, atrial fibrillation.