ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

ANALYSIS OF LOW HDL LEVELS AS A MAJOR RISK FACTOR OF ACUTE MYOCARDIAL INFARCTION IN PAKISTAN

Dr. Ambreen Khalid, Dr. Syed Ahmed Shahzad, Dr. Syed Mehmood Shahzad

Introduction: Myocardial infarction (MI) remains a leading cause of death worldwide. Myocardial ischemia occurs as a result of plaque build up in the coronary arteries, a disease formally known as atherosclerosis or coronary artery disease (CAD). Aims and objectives: The basic aim of the study is to analyse the low HDL levels as a major risk factor of acute myocardial infarction in Pakistan. Material and methods: This cross sectional study was conducted in DHQ teaching hospital Sahiwal during 2018 to 2019. The study was conducted according to the ethical committee of the hospital. The data was collected from 100 patients of both genders. The data was collected from those patients who visited the OPD of the hospital regularly. TC level in serum was measured using the endpoint test method. Results: The data was collected from 100 patients of both genders. The mean age was 45±5.46 years. The proportion of male subjects was higher in groups with high TG levels, while the difference in age was not statistically significant. With the increase in TG level, the proportion of people with a history of smoking increased, body mass index (BMI), SBP, DBP, FBG, UA and the rate of MI increased, while HDL-C level gradually decreased, and the differences were all statistically significant. Differences in TC and LDL-C levels were not statistically significant. Conclusion: It is concluded that low HDL level is noted to be present in a high percentage of acute myocardial infarction patients and can be a major risk contributor.

FULL TEXT