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TITLE:

A COMPARATIVE STUDY TO KNOW THE EFFICACY OF CRYOTHERAPY VERSUS 10% POTASSIUM HYDROXIDE SOLUTION IN THE MOLLUSCUM CONTAGIOSUM TREATMENT

AUTHORS:

Dr. Syed Bilal Ahmed*, Dr. Sajida Jabeen*, Dr. Zafarullah*

ABSTRACT:

Molluscum contagiosum (MC) is contagious viral infection that affects commonly children. A number of physical and chemical techniques are accessible for treatment. Objective: To estimate the safety and efficacy of 10% potassium hydroxide (KOH) solution versus cryotherapy in MC treatment. Study Design: A case-control study. Place and Duration: In the Dermatology department of Sandeman Provincial Hospital, Quetta for six months duration from February 2018 to July 2018. Methods: Into 2 groups: 40 MC infected children were divided. In A group (n = 20); Cryotherapy (a freeze chain cycle) was done or in B group (n = 20); 10% potassium hydroxide (KOH) solution was applied twice by the parents or patient up to 3 months. At the beginning of the study, at 2 weeks, 1month, 2 months and 3 months, the subjects were followed up to determine side effects or efficacy (defined as lesions disappear). Results: At the completion of the analysis, in A group, 14 patients (cryotherapy) and in B group 17 patients (KOH) were examined. In 14 patients (100%) of the cryotherapy group and in KOH group 16/17 (94.1%) had comprehensive lesions removal. Local side effects in group B (KOH) were 88.2% and in A group (cryotherapy) were hundred percent. Though, these were insignificant and did not justify treatment discontinuation. Conclusion: In children with MC 10% KOH solution is same effective treatment as cryotherapy. However, KOH is safer relatively and more patient-friendly therapy. Keywords: Potassium hydroxide, cryotherapy, molluscum contagiosum.

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