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TITLE:

THE REGULATION OF LIPID METABOLISM BY TARGETING OPIOID RECEPTORS IN NONALCOHOLIC FATTY LIVER DISEASE

AUTHORS:

Dr Ahmad Talal Asif, Dr Sheikh Muhammad Rehman Zia, Zahid Hussain

ABSTRACT:

Nonalcoholic greasy liver infection (NAFLD) is an outstanding hepatic ailment. The pathogenesis of NAFLD can be improved by the tweak of narcotic receptors to weaken hepatic lipid variations from the norm. It is without a past filled with liquor misuse, which shows a brokenness of the ordinary procedures of lipid blend and end in hepatocytes. Aggravation has been believed to be related with the development of nonalcoholic steato-hepatitis (NASH) and elevates the movement to hepatic fibrosis and liver cirrhosis. The recognizable proof of potential mixes by focusing on narcotic receptors in the improvement of NAFLD is promising. Narcotic receptors appear to be engaged with the guideline of lipid and vitality digestion. Narcotic receptors appear to be engaged with the guideline of lipid and vitality digestion. Key words: Nonalcoholic steatohepatitis; Opioid receptor; Hepatic steatosis; Inflammation; Endoplasmic reticulum.

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