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EFFICACY OF VITAMIN D IN CHILDREN WITH COMMUNITY ACQUIRED PNEUMONIA (CAP)

Dr Samra Liaqat; Dr Malik Abid Ali; Dr Asad Mahmood Khan

Objective: To determine the efficacy of vitamin D in children with community acquired pneumonia. Study design: Randomized controlled trial. Place and duration of study: The children Hospital and Institute of Child Health, Faisalabad during 15-05-2019 to 15-07-2019. Material and Methods: In this study the cases of either gender with age up to 12 years were included. The subjects were enrolled that were suffering from community acquired pneumonia, diagnosed by symptoms of fever, cough, sputum and non homogenous opacities on chest x ray. They were divided into two groups. The cases in group A were given vitamin D along with standard antibiotics and those in group B were given same quantity of the normal saline along with standard antibiotics. These cases were then followed to look for time taken to normalization of the CRP and also fro mean hospital stay. Results: In this study 100 cases were selected. 50 in each group. Mean age in group A and B was 7.13±1.23vs 7.34±1.31years and mean duration of symptoms was 2.23±1.47 vs 2.21±1.34 days. Mean hospital stay in group A and B was 4.11±1.53 vs 6.34±0.67 with p= 0.01 and mean time to normalization of CRP was 3.87±1.94 vs 6.23±3.11 days with p= 0.001. Conclusion: Vitamin D plus antibiotics is significantly better as compared to antibiotic and placebo in children with community acquired pneumonia. Key Words; CAP, Vitamin D, Antibiotics, CRP

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