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COMPARISON OF MEAN SERUM MAGNESIUM LEVELS BETWEEN THE PATIENTS WITH PRETERM LABOUR AND TERM LABOUR

Dr. Talat Perveen, Dr. Shazia Khanam, Dr. Saba Yasmeen Usmani

Objective: To compare the mean serum magnesium levels between the patients with preterm labour and term labour at tertiary care hospital. Material and methods: This case/control study was conducted at Department of Obstetrics & Gynecology, Bahawal Victoria Hospital, Bahawalpur from March 2018 to October 2018 over the period of 6 months. Study was approved by ethical committee and written informed consent was taken from every patient. The subjects included 100 pregnant women with preterm labour (cases) between 28 and 37 weeks gestation (Group A) and similar number of pregnant women with term labour (controls) between 37 and 40 weeks (Group B). Mean serum magnesium levels were compared between the both groups. Results: In present study total cases and 100 controls were selected. Mean age of cases and control was 24.96 versus 25.04 years. In age group <20 years, mean serum magnesium level in group A was 1.32±0.42 mg/dL and in group B was 1.3±0.47 mg/dL. Difference of mean serum magnesium level between both groups was statistically insignificant with p value 0.35. In age group 21-25 years, mean serum magnesium level of study group A was 1.13±0.41 mg/dL group B was 1.62±0.43 mg/dL. Difference of mean serum magnesium level between the both groups was statistically significant with p value 0.0001. In age group 26-30 years, mean serum magnesium level was 1.03±0.40 mg/dL and 1.51±0.50 mg/dL respectively in group A and B. Difference was statistically significant with p value 0.0002. In age group >31 years, mean serum magnesium level in group A was 1.01±0.30 mg/dL and in group B was 1.74±0.49 mg/dL. Difference was statistically significant with p value 0.002. Mean serum magnesium level of Primigravidas of group A and B was 1.18±0.41 mg/dL and 1.65±0.43 mg/dL respectively. Difference of mean serum magnesium level between the both groups was statistically significant with p value 0.0001. Among Gravida 2 and 3, mean serum magnesium level of group A was 0.88±0.29 mg/dL and group B was 1.32±0.46 mg/dL and the difference was statistically significant with p value 0.0002. Conclusions: Low maternal serum magnesium level is associated with preterm labour. Patients with preterm labour have significantly low serum magnesium level when compared with labour at term. Keywords: Maternal serum magnesium, Preterm labour, Term delivery.

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