::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

SCREENING OF SECONDARY METABOLITES, ENDOPHYTIC DIVERSITY AND ANTIMICROBIAL ACTIVITY OF ENDOPHYTES ISOLATED FROM AN ENDANGERED PLANT VATERIA INDICA (LINN) SARJA.

AUTHORS:

Mona., Y. L. Ramachandra*, and Pooja. R.

ABSTRACT:

The current study was aimed to evaluate the endophytic diversity and its biological activity of V. indica, an endangered plant. It is also known as white dammar, is a species of plant in the Dipterocarpaceae family. It is a slow- growing species, endemic and found predominantly in the south west coast evergreen forests. The majority of endophtyes are isolated from stem and leaves. The ethanolic extract of all endophytes shows antibacterial activity with maximum 20mm and a minimum of 4mm zone of inhibition against different bacteria in disc diffusion assay. From the present study we conclude that the compounds synthesized by bio endophytes are used for the treatment of many diseases. Screening of secondary metabolites which include alkaloids, flavonoids, saponins, terpenoids, steroids, glycosides, tannins, volatile eoils etc., are used for curing many diseases. Few isolates showed the maximum antimicrobial activity exhibiting the clearzone of inhibition against few human pathogens. Pharmacological studies have mainly focused on potential efficacy on tumors, bacteria, Alzheimer’s disease, cardiovascular diseases, and others. Keywords: V. indica, Secondary metabolites, Antimicrobial activity, Endophytic diversity.