::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ANTI-OXIDANT ACTIVITY OF SECONDARY METABOLITES PRODUCED BY FUSARIUM OXYSPORUM: AN ENDOPHYTIC FUNGUS ISOLATED FROM AN ENDANGERED PLANT MAPPIA FOETIDA

AUTHORS:

Pooja. R, Mona, Kumara hegde, B. A., Y. L. Ramachandra

ABSTRACT:

Endophytes are the excellent source for the production of bioactive natural compounds. Endophytic fungi were isolated from the endangered medicinal plant Mappia foetida. Fusarium oxysporum has been cultured and identified. Qualitative assay of the bioactive natural compounds was investigated by using standard protocol. The extract was screened for possible antioxidant activities by free radical scavenging activity (DPPH). Hence this study showed promising DPPH (1, 1-diphenyl-2-picrylhydrazyl) scavenging activity for F. oxysporum. The endophytic fungal leaf extract of F. oxysporum showed highest antioxidant activity around 74.46% which has scavenging effect on DPPH assay. Keywords: Fungal endophytes, Bioactive natural compounds, DPPH (1, 1-diphenyl-2-picrylhydrazyl) scavenging activity.