::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

INHALATION OF HYDROGEN GAS WITH RELATION TO OXIDATIVE STRESS IN ASTHMA

AUTHORS:

Dr Muhammad Furqan Ismat Virk, Muhammad Hamza Noon, Dr. Qasim Niaz

ABSTRACT:

Introduction: Oxidative stress is implicated in the pathogenesis and progression of asthma, chronic obstructive respiratory disease (COPD), and cystic fibrosis (CF). Reactive oxygen species are unstable compounds with unpaired electrons, capable of initiating oxidation. Aims and objectives: The basic aim of the study is to measure the level of antioxidants and inhalation of hydrogen gas which relation to oxidative stress in asthma. Methodology of the study: This cross sectional study was conducted at DHQ hospital, Hafizabad during 2019. All the data was collected according to the rules and regulations of authority. The data was collected from both genders which suffer from asthma. The blood was drawn from all patients for further analysis of antioxidants. Results: Mean values of investigated parameters and diﬀerences in the values between, before and after inhalation of hydrogen gas. The values are expressed in terms of mean± SD. According to the analysis, the level of SOD, MDA and GSH increase as compared to normal level. But the level of catalases decreased with the value of 0.43±0.39. Conclusion: It is concluded that inhalation of hydrogen gas can imbalance the level of antioxidants in the blood in asthma diseases.