::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ROLE OF CBC IN GASTROINTESTINAL CANCER

AUTHORS:

Dr Zulaikha Ayub, Dr. Maria Munir, Dr. Hira Khalil

ABSTRACT:

Introduction: Cancer is a leading cause of death worldwide: it accounted for 7.9 million deaths (around 13% of all deaths) in 2008. The rising life expectancy means that the risk of developing cancer is also increasing. Gastric cancer is the second most common cancer worldwide and almost two-thirds of all cases occur in developing countries. Objectives of the study: The basic aim of the study is to analyze the complete blood count (CBC) in gastrointestinal cancer patients. Methodology of the study: This descriptive study was conducted at Fatima Jinnah medical University, Lahore during 2019. The data was collected from both genders and the sample size is 70. Detailed history was taken from all patients with special reference to duration of disease, mode of infection, previous history of disease, HBV or HCV or any other kind of infection. A thorough clinical examination was carried out and stigmata of disease and histopathology was noted. Results: According to analysis CBC of patients shows that the level of WBCs and RBCs become decreases in gastrointestinal cancer. It shows that GSH level become increases in patients as compared to control. But the GPx become decreases. All other antioxidants become increases in patients group as compared to control. Conclusion: It is concluded that the level of antioxidants will be used as an important biomarker in the diagnosis and treatment of gastrointestinal cancer. And the level of blood cells become decreases in diseased condition.