::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

HEMATOLOGICAL VARIATIONS AND PRESENTING COMPLAINTS IN PATIENTS WITH POSITIVE MALARIAL PROFILE

AUTHORS:

Dr Shah Zaib, Dr Hafiz Hamad Siddique, Dr Qasim Zahoor

ABSTRACT:

Objective: To assess hematological changes and report symptoms in people with positive malaria result. Methods: A total of 200 people with symptoms of malaria were collected from outpatient departments of Jinnah Hospital Lahore for one-year duration from March 2019 to March 2020. People taking antimalarial drugs were excluded from the study. 2.0 ml of venous blood was withdrawn aseptically into a sterile, appropriately labeled EDTA vial. Hb, TLC, platelet counts were performed using Sysmex XT 1800i automated blood counters. The collected data was entered and analyzed in SPSS version 15.0. P-value was calculated between two means. Results / Conclusions: Among these 200 patients, the malaria-positive cases (Group 1) with both staining methods were 170 (85%) and the malaria-negative cases (Group II) were 30 (15%). Hb was lowered in MP + ve cases, but the statistical difference was not significant. TLC was reduced in MP + ve cases compared to MP negative cases, showing a significant statistical difference. Platelet counts were reduced in MP + ve cases compared to MP + negative cases, showing a statistically significant difference. Key words: Malaria, hematological changes, symptoms.