Aim. In dentistry treatment at any stage, an unwanted accident may occur due to the malpractice of the dentists which can be due to the compromise in the endodontic treatment. The main objective of this study is to observe and analyze the behavioral conduct of the dentist related to ethical concerns toward perforation and separation of endodontic instrument during the treatment of root canal in Pakistan. Method. Among the dentist working in private, government and university clinics well-structured and organized 111 questionnaires were distributed. The collected data was thoroughly reviewed and SPPS software used to analyze the data. Moreover, chi-square tests and fisher’s exact methods were used to analyze the collected data. Results. According to 54.9% of the respondents, they may inform the patients about his accident during treatment. During the treatment of root canal 43% patients experienced perforation.53.3% replied that they would tell the patients about the separation of instruments. Moreover 54.5% participants had experienced instrument separation Conclusion. As this survey was limited due to its limited participants however this survey concluded that most of the dentist inform patients in case on any accident and they are well aware of the ethical concerns related to dentistry and did not hesitate to use them to avoid malpractice.