::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

UROTHELIAL CARCINOMA; HISTOLOGICAL GRADING AND ASSOCIATION WITH GENDER

AUTHORS:

Dr Pervez Ahmed, Dr. Jamil Ahmed, Dr. Hayat Kakar, Dr Ghulam Sarwar

ABSTRACT:

Objective: Objective of this study is to determine frequency of urothelial carcinoma according to histological grading among male and female population Design and duration: Retrospective study. Duration from January to December 2019 Setting: Study was conducted at Urology department of Bolan University of Medical and Health sciences Patients and methods: Patients having urinary bladder admitted in urology ward, planned for transurethral resection of bladder tumor, were included in this study using non probability consecutive sampling technique. After transurethral resection of bladder tumor paraffin-embedded and formalin-fixed four micrometer thick sections were prepared for histological examination. All data was documented on a self-made proforma. Means, frequency, standard deviation, percentages and p-value calculated using SPSS software version 24. Results: Total 110 cases, including 60.9% male and 39.1% female cases were diagnosed with urothelial carcinoma on histopathological examination. Age range of cases was 30-70 years with mean age of 51.4±6.2 years. Maximum patients (38.2%) were between 30-40 years of age. Conclusion: Urothelial carcinoma is much prevalent among male population but severity of disease is more among female population. No significant association was seen with age. Key words: Urothelial carcinoma, histological grading, transitional cell carcinoma, gender, age