::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ANALYSIS OF IMPORTANCE OF ZINC SUPPLEMENTATION IN THE TREATMENT OF PNEUMONIA IN CHILDREN AGED 2 TO 5 YEARS

AUTHORS:

Dr. Asif Khan, Dr. Rida Fatima, Dr. Hafiza Zarka Yaqoob

ABSTRACT:

Aim: The aim of the study was to compare the average duration of treatment with and without zinc supplements as an adjunct to antibiotic therapy of pneumonia in children aged 2 to 5 years. Study Design: A randomized controlled trial. Place and Duration: The study was conducted in the Pediatric Medicine department of Capital Hospital, Islamabad for one year duration from May 2019 to April 2020. Method: A non-probability purposive sampling technique was used in this study. After approval by the hospital's ethics committee, 150 children meeting the selection criteria were registered. Parental consent was obtained. Demographic data (age, name, address and gender) was obtained. The children were divided randomly into 2 groups by the lottery method. Group A received only standard antimicrobial therapy (ceftriaxone). Group Z received zinc as adjunct therapy and standard antibiotics (ceftriaxone). Oral zinc was administered in doses of 10 mg once a day to children less than one year and 10 mg two times a day to children over 1 year. Recovery time was observed from the start of treatment until the symptoms disappeared. Both groups were compared for mean recovery time using an independent sample t.e <0.05 was considered significant. Results: 150 cases were selected for the study. The children average age was 29.14 ± 16.60 months, and the minimum and maximum age was 2 months and 5 years. The results of the study showed that 47% of patients are men and 53% are women. 75 (50%) patients with temperature resolution and 75 (50%) patients without temperature resolution appeared in this study. While solubility of tachypnea was observed in 65% of patients, it was not observed in 35% of patients. Conclusion: Adding zinc as an adjunct to typical treatment of pneumonia is beneficial in reducing the course of treatment. In addition, it is useful to shorten the duration of the symptoms of the disease. Key words: children, duration of treatment, pneumonia, standard antibiotic, zinc supplement.