::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

TO DETERMINE THE FREQUENCY METABOLIC FACTORS AMONG NON -ALCOHOLIC FATTY LIVER DISEASE (NAFLD): A CROSS-SECTIONAL STUDY

AUTHORS:

Dr Sohaib Amin, Dr Faizan Banaras, Dr Sadia Talib

ABSTRACT:

Objective: The aim of the study is to determine the frequency of factors leading to metabolic syndrome among non -alcoholic fatty liver disease (NAFLD) patients at a tertiary care hospital. Study Design: Descriptive cross-sectional study. Place and Duration of Study: This study was conducted in department of Medicine, Services Hospital, Lahore and was carried out over a period of one year from 1st May, 2019 to 30th April, 2020. Material and Methods: A total of 110 patients were included in this study. History was taken to rule out alcohol intake, viral and drug induce d etiology, to determine the presence of co -morbidities like obesity, type 2 diabetes mellitus, arterial hypertension and dyslipidemia. Physical examination was carried to determine the arterial blood pressure and to determine anthropometric data that is weight, height, body mass index (BMI) and abdominal obesity by measuring waist circumference. Results: Mean age of the patients was 49.95 ± 8.86 years. There were 72 male patients (65.5%) while 38 (34.5 %) patients were female. Different metabolic factors were central obesity in 82 patients (74.5%), raised high density lipoprotein (HDL) in 19 patients (17.3%), raised cholesterol in 87 patients (79.1%), raised blood pressure in 65 patients (59.1%) and raised fasting plasma glucose in 82 patients (74.5%). Mean BMI was 26.31 kg/ m 2 ± 2.68, mean waist circumference was 109.82 cm ± 18.41, mean cholesterol was 237.50 ± 48.47mg/ dl , mean systolic blood pressure was 148.88 mmHg ± 22.10, mean diastolic blood pressure was 90.41mmHg ± 12.25 and mean fasting plasma glucose was 113.28mg/ dl ± 22.80. Stratification regarding age was carried out. Conclusion: A considerable number of patients with NAFLD had metabolic syndrome. There was a close correlation between NAFLD and metabolic syndrome. Keywords: IDF criteria, Metabolic syndrome, Non-alcoholic fatty liver disease.