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TITLE:

THE EFFECT HYDRO-ALCOHOLIC EXTRACT OF YARROW (ACHILLEA OFFICINALIS) ON BLOOD FACTORS OF FEMALE LABORATORY MICE

AUTHORS:

Shabnam Hassanzadeh Roohalai , Mehrdad Modaresi *

ABSTRACT:

Yarrow (Achillea officinalis) is one of the plants from the Asteraceae family. In fact, it is one of the most famous medicinal plants that boosting the immune system is one of its benefits. Current research was carried out to study the effect of hydroalcoholic extract of yarrow (Achillea officinalis) on blood factors of female laboratory mice. Fifty female mice were divided into five groups including control group, placebo and three treatment groups which received 50, 100 and 200 mg/kg of hydroalcoholic extract injections in peritoneum for twenty days every other day. After twenty days blood samples were taken from the heart the number of blood cells were measured using an automatic cell counter machine. Results showed that the number of white blood cells, lymphocytes and monocytes were increased significantly in 50 all treatment groups in proportion to control group. WBC was increased in 50 mg/kg group showed significantly increase. The number of RBC was significantly increased by 200 mg/kg dose whereas the number of neutrophils was decreased significantly in all three doses. According to results, yarrow extract showed a significant effect on blood factors in all three doses and can have a positive effect on the number of red blood cells and white blood cells Keywords: Yarrow, Blood factors, Laboratory mice

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