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A REVIEW ON PROBIOTICS AS IMMUNOMODULATORS

Gitesh Nana Guthale, Hemant Pramod Vanjari, Mitali Vijay Dalvi, Hitesh Vinayak Kachave, Mahalaxmi Mohan.

The present study focuses on various aspects of probiotics and their effects on immune system. Probiotics are live organisms which when taken in adequate amount imparts therapeutic effects on the host. The probiotics are obtained from various sources of microbes mainly from Lactobacilli and Bifidobacteria species. Probiotics acts on both types of immunity i.e adaptive and innate immunity and are responsible to activate T-cells, B- cells, NK cells which protects the body from various infections. Overall probiotics can be used in prevention/treatment of various types of diseases such as diarrhoea, ulcerative colitis, Irritable bowel syndrome etc. without disturbing the microbial balance of the body. Keywords: Probiotics, Immune system, Immunomodulators.

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