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TITLE:

ANALYSIS OF FREQUENCY OF LOW SERUM FERRITIN LEVEL IN PATIENTS OF DECOMPENSATED CHRONIC LIVER DISEASE

AUTHORS:

Dr Muhammad Asad Butt, Dr Zia Ul Mustafa, Dr Sameen Inam

ABSTRACT:

Introduction: In Pakistan more, people die of liver disease due to chronic hepatitis every day than terrorism in a year. Aims and objectives: The main objective of the study is to analyse the frequency of low serum ferritin level in patients of decompensated chronic liver disease. Material and methods: This cross-sectional study was conducted in Aziz Bhatti Shaheed Teaching Hospital, Gujrat during May 2018 till November 2018. The data was collected from 100 patients. All adult and middle age 20-60 years patients of both genders diagnosed case of chronic liver disease (previously or recently diagnosed having features of decompensated disease) were included in the study. After clinical examination, the diagnosis of chronic liver disease was made. After taking all aseptic measures blood was taken and stored in a serum bottle. Results: The data was collected from 100 patients. Mean age (years) in the study was 53.74+8.66 with ranges from 20 to 60 years. Distribution of gender of patient was also calculated in terms of frequency and percentage of male and female patients. There were 03 (1.8) patients have low serum ferritin level (< 20 ng/ml) and decompensated chronic live disease secondary to hepatitis C virus infection. Similarly, descriptive statistics of serum ferritin (ng/ml) of patient was also calculated in terms of mean and standard deviation. Mean serum ferritin level in the study was 200.33+196.97. Conclusion: It is concluded that elevated serum ferritin worsened liver injury. Hence it represents early marker for the severity of chronic liver disease, related both to the degree of liver fibrosis and to the inflammatory activity

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