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ANALYSIS OF RELATION OF 1,25-DIHYROXYVITAMMIN D AND ITS PROTEIN IN PERIODONTITIS

Dr Mahnoor Asif, Dr Saad Maqsood, Dr Aamna Islam

Introduction: Periodontitis is inflammation of the supporting tissues of teeth resulting in gingival detachment and disintegration of alveolar bone. Aims and objectives: The main objective of the study is to analyze the relation of 1,25-dihyroxyvitammin D and its protein in periodontitis. Material and methods: This cross-sectional study was conducted in Demontmorency College of Dentistry, Lahore during November 2018 to March 2019. The data was collected from 100 patients of both genders. The data was collected for the analysis of relation of vit-D ad its binding protein with periodontitis. The data was collected through a properly designed questionnaire. This was including all the demographic data and medical data of patients. Results: The data was collected from 100 patients. The mean age of participants was 31.23±2.70 years and was not significantly different between the two groups. The oral health indices including gingival index, plaque index, calculus index, mobility index, CAL and PPD, were significantly higher in cases. The mean DBP levels in mild periodontitis were 65.33±91.90 ug/mL and significantly increased along with the severity of periodontitis (p=0.005). Conclusion: It is concluded that the levels of DBP increased significantly along with the severity of periodontal destruction and may be used as a biomarker to complement the diagnosis of periodontitis in early as well as late stages.

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