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Laraib Ali, Maryam Majeed, Dr Alia Ramzan


Objective: To assess the impact of post-myocardial dead tissue Streptokinase treatment on myocardial practicality, utilizing Thallium-201 single photon outflow computed tomography (TL-201 SPECT). Design: Review, exploratory think about. Place and duration of study: The Cardiology Division, Outfitted Powers Organized of Cardiology, Services hospital lahore from 1st April 2018 to 31st October 2018. Patients and Methods: Male patients, who had endured from intense myocardial dead tissue (AMI), in a region provided by the cleared out front slipping (Chap) supply route, had infarct-related electrocardiogram (ECG) changes and gotten or did not get Streptokinase treatment, were included. Those with an ordinary ECG, or history of revascularization, or non-ST rise MI, or more than one MIs, were avoided. The patients were separated into bunches 1 (who gotten Streptokinase) and 2 (who did not get Streptokinase). Each bunch contained 42 patients and all experienced scintigraphy practicality ponder through intravenous infusion of 3.0 mCi (123 MBq) of TL201, taken after by rest-redistribution SPECT imaging on a double head, devoted cardiac gamma camera framework (Philips Cardio MD ®). Emory’s cardiac tool kit ® and Auto QUANT ® were utilized for information handling and quantitative estimation of reasonable myocardium. Observational scores from to 2 were doled out to each of the looks, within the arrange of expanding reasonability, and these were compared over the two bunches. Result: Bunch 1 contained 42 patients (age run = 38 to 80 a long time, cruel = 53.98 ± 11.26 a long time), in whom experimental practicality scoring was done. Score was seen in 2 patients, score 1 was seen in 15 patients and score 2 was seen in 25 patients shape this bunch. Gather 2 too contained 42 patients (age run = 38 to 80 a long time, cruel = 56.71 ± 9.05 a long time), in whom reasonability score of was seen in 3 patients, score 1 was seen in 11 patients and score 2 was seen in 28 patients frame this gather. Age contrast between the two bunches was factually inconsequential (p = 0.223). The myocardial reasonability comes about dissected by 3 x 2 possibility table applying chi-square (χ²) test too appeared no critical distinction between bunches 1 and 2 (p = 0.611). Conclusion: This think about did not discover any critical contrast in myocardial practicality – post myocardial dead tissue – in patients who gotten or did not get Streptokinase treatment. Keywords: Streptokinase treatment, Thallium-201, SPECT, myocardial reasonability, single photon emanation computed tomography.


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