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TITLE:

A RETROSPECTIVE STUDY TO ANALYZE THE EFFICACY OF RADIOACTIVE IODINE (RAI) FOR THE TREATMENT OF HYPERTHYROIDISM

AUTHORS:

Dr Qurat ul Ain, Dr Ayesha Asad, Dr Shehar Bano

ABSTRACT:

Objective: To investigate the results of radioactive iodine (RAI) in the treatment of hyperthyroidism. Study design: A retrospective study. Location and Duration: This study was conducted in the Medical Department of Holy Family and DHQ Hospital, Rawalpindi for one year duration from January 2018 to December 2018. Method: In this study total of 216 patients were treated by Radioactive iodine. It has been shown to possess hyperthyroidism with function test (T3, T4 and TSH) and isotope discovery of the thyroid gland. RAI in 10 mci was given to all of them and were followed up for at least a year later one month later and every two months. The efficacy of the treatment was evaluated by thyroid function tests clinical features improvement. Findings: 216 total patients were observed, 37.01 ± 11.24 years was the average age. Women were 153 and males were 63. In 164 patients [66.05%] Graves' disease was noted, 37 patients [25.1%] have toxic multinodular goiter and 16 patients [9.3%] toxic adenoma. After one month only Symptoms improved in 11 patients, but for two months others needed antithyroid therapy. After 6 months treatment only 17 patients have hyperthyroidism. Conclusion: For hyperthyroidism treatment radioactive iodine is very effective but has side effects such as fatigue, hypothyroidism and weight gain. Keywords: Radioactive iodine, hyperthyroidism.

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