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ASSOCIATION OF COUNT OF WHITE BLOOD CELLS, COUNT OF ABSOLUTE NEUTROPHIL IN CHILDREN SUFFERING FROM FEVER DUE TO INFECTIONS OF BACTERIA

Dr Hafiz Muhammad Hammad Yaqub, Dr Junaid Hussain,

Objectives: This research work aimed to study the association count of WBC (white blood cells), ANC (absolute neutrophil count in feverish children from one to eighteen months of age as prognosticator of the infection due to bacteria, so to improve the expectedness of infections because of bacteria in emergency to reduce the preventable admissions & use of the antibiotics. Methodology: Retroactive review carried out on feverish children from one to eighteen months of age who got admission in the General Hospital Lahore from August 2018 to March 2019 on the probable identification of the fever with no focus. Whole septic work-up carried out for every patient in accordance with the protocol of the local hospital including complete count of the blood, culture of blood, culture of urine, X-ray of chest & lumbar puncture. Patients who found with the previous antibiotic usage history within forty-eight hours of admission were not the part of this research work. We reviewed the data regarding history, laboratory testing, physical examination & radiology carried out. Information regarding age, gender, fever, availability or non-availability of the infection due to bacteria, white blood cells count, absolute neutrophil count, report of chest X-ray & culture of the body result’s collection carried out for analysis. Results: We reviewed 34 patients in this research work. Total 23.50% (n: 8) patients were available with infection of bacteria: categorized as Group-1 (two pneumonias, three infection of the urinary tract, two meningitis, one occult bacteremia) & 76.50% (n: 26) patients fund with no proof infection due to had no evidence of bacterial infection, categorized as Group-2. There was no important disparity available between the members of both groups regarding age, fever, gender & white blood cell count whereas there was an important disparity among the patients of both groups about absolute neutrophil count and there was better sensitivity (78.0%) & specificity (89.0%) of ANC in comparison with the white blood cell count (sensitivity 77.0% & specificity 62.0%). Conclusion: Absolute neutrophil count is very good prognostic test for the determination of the infection due to bacteria in the young feverish children with no focus. But sill there is requirement for other more consistent fast and cheap method for dealing with the young feverish children at the department of emergency. KEY WORDS: Neutrophil, Prognostic, Feverish, Determination, Consistent, Pneumonia, Sensitivity, Specificity.

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