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ASSESSMENT OF BIOCHEMICAL SALIVARY PROFILE IN TYPE 2 DIABETES MELLITUS IN PAKISTAN

Dr Maria Younas, Dr Iqra Javid, Dr Mudassar Nazir, Dr Hussain Zia

Introduction: Diabetes mellitus is a public health problem since, in addition to important social repercussions. It is a chronic disease that affects a growing number of individuals from different countries which are at different stages of economic and social development. Aims and objectives: The basic aim of the study is to analyze the salivary profile in type 2 diabetes mellitus in Pakistan. Material and methods: This cross sectional study was conducted in Allama Iqbal Memorial Teaching Hospital, Sialkot during April 2018 till November 2018. The data was collected from 100 patients. The data was collected into two groups. We divided the data into two groups. One was control group and one was diseased group. The data was collected through a questionnaire. Questionnaires which requested details of demographic data and medical history were administered to the subjects, following which saliva was collected from them in the morning between 7 am–8.30 am in the fasting state. Results: The data were collected from 100 patients. The mean age of the participants in the study was 46.5 years. No significant differences were observed between the sexes in both groups in pH, salivary flow rates and biochemical parameters. Glucose, urea, calcium, anti-S.mutans IgA, total IgA and anti-insulin IgA were significantly higher in diabetic patients (p < 0.05). On the other hand, total protein and amylase concentrations were significantly lower in diabetic patients (p < 0.05). Conclusion: It is concluded that there is a significant variations in both physical and biochemical parameters of saliva in T2DM, some salivary parameters were found to be useful to classify an adult as diabetic.

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