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A CASE CONTROL STUDY TO KNOW THE ASSOCIATION BETWEEN HELICOBACTER PYLORI INFECTION AND HEPATIC ENCEPHALOPATHY

Dr Muhammad Sajjad, Dr Said Ali, Dr Ejaz Ahmad

Information on the pathology of Helicobacter pylori (H. pylori) in human liver and biliary tract diseases is vast. Objective: The purpose of this analysis is to evaluate the possible relation between hepatic encephalopathy and H. pylori seropositivity. Study Design: A case control study. Place and Duration: In the Gastroenterology Department of Lady Reading Hospital, Peshawar for one-year period from January 2018 to December 2018. Methodology: These three groups are a case-control study with cirrhotic patients with non-HE cirrhotic patients hepatic encephalopathy (HE) and healthy controls. Based on ELISA investigation all subjects were serologically examined to determine IgG class antibodies against H. pylori. Results: H. pylori positivity Hepatic encephalopathy cirrhosis was present in 86% of patients with cirrhosis without hepatic encephalopathy and 88% of patients with a healthy control of 66%. Conclusion: H. pylori seropositivity incidence according to our analysis in cirrhotic patients with and without hepatic encephalopathy was greater than healthy controls. However, H. pylori seropositivity was not vastly distinct between cirrhotic patients with non-cirrhotic patients and hepatic encephalopathy. Key words: cirrhosis Hepatic encephalopathy, H.pylori infection, GIT Diseases.

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