::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

INCIDENCE OF DUODENAL ULCER IN LIVER CIRRHOSIS

AUTHORS:

Dr. Manseba Zahid, Dr. Murtaza Khan, Dr. Asma Aslam

ABSTRACT:

Introduction: Liver cirrhosis is a common cause of duodenal ulcers. Cirrhosis causes portal hypertension, splenomegaly, esophageal varices (EV) and duodenal ulcer. Bleeding from duodenal ulcers is a serious complication with significant morbidity and mortality. Therefore, it is recommended that patients with cirrhosis be examined for the presence of duodenal ulcer at the time of initial diagnosis and periodically throughout their lives. Duodenal ulcer can cause fatal bleeding in patients with cirrhosis, emphasizing that duodenal ulcer should be monitored as the cause of bleeding rather than esophageal varices. This study aims to show the relationship between duodenal ulcers in patients with cirrhosis as presented in Medical Department. The implementation of its results may help in the early treatment of life-threatening upper gastrointestinal bleeding. Aim: To determine the frequency of duodenal ulcers in patients with cirrhosis. Study design: A cross-sectional study. Place and Duration: In the Medicine Unit of Services Hospital Lahore for one year duration from April 2019 to April 2020. Methods: The study included one hundred patients with liver ecotoxicity in the abdominal ultrasound examination and meeting the inclusion criteria. These patients then performed endoscopy of the upper gastrointestinal tract after informed consent and the presence and number of duodenal ulcers were noted. The location of the ulcer, its size and whether the ulcer was bleeding was also noted. Results: The incidence of duodenal ulcers in patients with cirrhosis was 9.6%. Conclusion: The study showed that 9.6% of patients with cirrhosis had a duodenal ulcer. Its use will help identify the cause of bleeding in patients with cirrhosis and help in treatment during endoscopy of the upper gastrointestinal tract. Key words: liver cirrhosis, duodenal ulcer, upper gastrointestinal endoscopy.