- CODEN : IAJPBB
- issn 2349-7750
TITLE:
MALIGNANT CAUSES OF SURGICAL JAUNDICE: A SINGLE CENTER STUDY
AUTHORS:
Qurat-ul-ain, Zohaib Zaheer, Sana Maqsood
ABSTRACT:
Surgical jaundice is a common surgical issue that is caused by an obstruction to the passage of conjugated bilirubin from liver cells to the intestine. Surgical jaundice management has been posing diagnostic and therapeutic challenges to general surgeons specially working in countries with limited resources. Jaundice owing to biliary obstruction can occur by different group of diseases that may be either benign or malignant. OBJECTIVE: To determine the frequency of malignancy and its types in patients presenting with surgical jaundice in a tertiary care hospital. STUDY DESIGN: Cross-sectional Survey. SETTING: Surgical ward, Allied hospital Faisalabad DURATION OF STUDY: Six month from Oct, 2018 - April 11, 2019 DATA COLLECTION PROCEDURE: The patients fulfilling inclusion criteria were admitted from out-patient department. The diagnosis of surgical jaundice was made on the basis of history, clinical examination, hematological and biochemical reports and radiological investigations. The patients were admitted in north surgical ward. The patients was further investigated and managed according to the guidelines. A written informed consent was collected before the study. All patients were managed as per guidelines for surgical jaundice with injection Vitamin K intramuscular, well hydration with intravenous fluids, avoidance of constipation by lactulose or neomycin, vitals and urine output monitoring and prophylactic antibiotics. The demographic information including name, age, gender, address and outcome variable (frequency of malignancy in patients presenting with surgical jaundice) was collected through proforma. RESULTS: The mean age of patients was 49.96 ± 16.54 years with minimum and maximum age as 18 and 80 years. There were 51(53.7%) male and 44(46.3%) female cases. A total of 19(20%) cases had BMI < 30 and 76(80%) cases had BMI ≥ 30. A total of 50(52.6%) cases had malignancy and 45(47.4%) cases were not diagnosed of malignancy. Among malignancy, 14(28%) cases had CA Gallbladder, 4(8%) cases had CA head of Pancreas, 9(18%) cases had Peri-ampullary carcinoma, 7(14%) case had Cholangiocarcinoma, 6(12%) cases had Klastkin tumor, 5(10%) cases had Hepatocellular carcinoma and 5(10%) cases had Metastatic tumor. CONCLUSION Through the findings of this study more than half of the cases i.e. 52.6% cases had malignancy in patients presenting with surgical jaundice. The most common type of malignancy was CA Gallbladder (28%) followed by Peri-ampullary carcinoma (18%), Cholangiocarcinoma (14%), Klastkin tumor (12%), Hepatocellular carcinoma and Metastatic tumor (10%)each, and CA head of Pancreas (8%). So, keeping high frequency of malignancy in mind and the clear picture in of its types patients with surgical jaundice must be treated accordingly to have a better prognosis. Keywords: Surgical jaundice, FNAC, malignancy, Gallbladder, Peri-ampullary carcinoma, Klastkin tumor, Hepatocellular carcinoma, Metastatic tumor, Pancreas
FULL TEXT
Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
Indexed In
S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
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