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TITLE:

SERUM COPPER LEVELS IN PATIENTS WITH ISCHEMIC HEART DISEASE

AUTHORS:

Dr. Wajeeha Khalid, Dr. Hafiz Muhammad Ihsan Majeed, Dr. Atif Kamal

ABSTRACT:

Aim: To compare serum copper levels in patients with coronary heart disease & healthy controls. Place and Duration: In the Department of Cardiology, Jinnah Hospital Lahore for one year duration from January 2019 to December 2019. Methods: This was a prospective case control study. In total 125 male participants were divided into a control group (n = 25), cases of ischemia without a heart attack (n = 50) and cases of ischemia with previous or current heart attack (n = 50). The study included patients who participated from OPD and inpatient department of cardiology. Serum was analyzed for copper by atomic absorption spectrophotometry. The acceptable reference range for serum copper is 70-140 µg / dl. Results: The average age of patients with coronary heart disease without myocardial infarction (group A) and myocardial infarction (group B) was 52.1 ± 1.22 and 50.74 ± 1.12, respectively. The mean age in the control group was 49.36 ± 2.01 years. Ischemic heart disease family and smoking history were more common among diseases than in the control group. Serum copper meditation was originate to be suggestively advanced in the studied subgroup B-2 (168.28 ± 7.84 micrograms / dl) compared to the control group (141.12 ± 6.43 micrograms / dl), and the other study groups showed slight differences in serum copper levels. Conclusion: Increased copper levels after acute myocardial infarction may have an effect rather than the cause of the disease. Key words: serum copper, ischemic heart disease, acute myocardial infarction, angina pectoris

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